Table of Contents December 2022 Issue #473


Letter from the Publisher

Jonathan Collin, MD

TL’s publisher considers the possibility that rapamycin has anti-aging properties, highlights the cover article about an alternative method for treating low testosterone, and asks for some much needed support.


Shorts

Jule Klotter
This month’s column looks at the use of intermittent stress to slow aging, DNA methylation patterns to assess aging, the link between systemic inflammation and oral health, and Paul Marik’s sepsis protocol.


Literature Review & Commentary

Alan R. Gaby, MD
Iodine insufficiency in pregnant women, melatonin to improve sleep in children with autism, Helicobacter pylori and iron deficiency, evening primrose oil for diabetic neuropathy, and more are the topics in this month’s column.


ON THE COVER

Stimulate Endogenous Testosterone in Late-Onset Hypogonadism

Alan B. McDaniel, MD
Since 2005, Alan McDaniel, MD, has been presenting his two-day course “New Endocrinology” to physicians on five continents. In this issue, he explains how to identify and treat late-onset hypogonadism without testosterone replacement therapy, which depresses gonadotropic stimulation and leads to negative effects.


A Comprehensive Approach to Sexual Function

Judson Brandeis, MD
A urologist who specializes in men’s health explains his comprehensive treatment for men with erectile dysfunction that improves cardiovascular health as well as intimacy and sexual function.


Mortality Reduction in Diabetics with PDE5 Inhibitor, Statin, and Testosterone Combination

Jeffrey Dach, MD
A combination of testosterone and two drugs approved for other conditions can reduce mortality in men with diabetes.


Why 5-Alpha Reductase Inhibitors Should Be Avoided for Prostate Urinary Problems and Nutraceutical Options

Geo Espinosa, ND, LAc
Botanicals and lifestyle measures provide an alternative to drugs that are prescribed for urinary tract symptoms associated with benign prostatic hyperplasia.


Testicular Cancer: An Update

Pamela W. Smith, MD, MPH, MS
This article outlines the risk factors, conventional treatments, and integrative measures for the most common solid tumor affecting males between 15 to 34 years of age.


Atherosclerosis I: Reduction, Nattokinase, Digital Pulse Wave Analysis

Davis W. Lamson, MS, ND
In-office research from Tahoma Clinic indicates that long-term use of nattokinase reduces arterial stiffness, confirming a 2017 Chinese study.


The Effectiveness of Platelet Rich Plasma for Joint Injury Repair

Peter A. Fields, MD, DC
Platelet rich plasma is part of a comprehensive regenerative orthopedics program used to treat damaged or weakened ligaments, tendons, and other soft tissues in joints.


Vitamin D and Covid-19: This Nutrient’s Potentially Pivotal Role in Combating Coronavirus

Jill Carnahan, MD
SARS-CoV-2 dysregulates the immune system and depletes vitamin D, which is, itself, a potent regulator of immune system function – making the vitamin an important element in treating patients with the virus.


Genetics, Hypertension, and Cardiovascular Disease

Mark Houston, MD
Identifying a patient’s genetic SNPs related to cardiovascular disease and hypertension can provide clear guidance on the type of diet, supplements, and even anti-hypertensive drugs that will be the most effective treatment.


Botanical Approach to Hydrogen-Positive SIBO: A Case Report

Samantha Davison and Bradford Case, ND, DC
This case report from Bastyr University California follows the diagnosis and naturopathic treatment of a young man with a long history of abdominal discomfort and dry skin.


Environmental Medicine Update

Marianne Marchese, ND

Allergies, Asthma, and the Air We Breathe
Avoiding poor air quality – as much as possible – is an important part of managing asthma and allergies.


Pediatric Pearls

Michelle Perro, MD

A Painless Approach to Pain in Children
Homeopathy is a valuable tool for helping children who are experiencing pain – whether the pain comes from teething, a skateboard injury, or a medical treatment.


The Lobay Viewpoint

Douglas Lobay, BSc, ND

Zinc, Antiviral Effects, and the Common Cold
Multiple studies have shown the value of this trace mineral, which the body needs to fight viral infections – including the common cold.


Calendar of Events

Curmudgeon’s Corner

Jacob Schor, ND, FABNO

Does Exercise Intensity Matter?
Although high intensity interval training is being promoted as providing better protection against premature death than moderate exercise, a close look at the research finds little difference between the two.


List of Advertisers in this Issue


Editorial

Alan R. Gaby, MD

Medical Education or Advertisement
Increasingly, researchers or their sponsors are paying journals to publish their papers in medical journals, leading to the increased risk of conflict of interest and bias.

Online Only

Listening to the Founding Fathers of Orthomolecular Medicine

by Dwight Kalita, PhD

Three pioneers in orthomolecular medicine encouraged the author to address his and his son’s susceptibility to respiratory infections, due to a congenital disease, with optimal nutrition and supplements – changing their health and their lives.


Degenerative Myelopathy Successfully Treated with Thiamine

by Robert Feller

The use of mega doses of vitamin B1 (thiamine) has restored function and, so far, prevented paralysis in the author’s German shepherd, who was diagnosed with a genetic spinal cord disease similar to Lou Gehrig’s disease.