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A novel view of cause and cofactors
in autoimmune dysregulation in Rheumatoid Arthritis, Multiple Sclerosis,
Ankylosing Spondylitis, Lupus and other autoimmune syndromes. This
article presents an integrated view of cellular energetic factors
participate autoimmune targeting with B-Cell lines through Tumor
Necrosis Factor targeting common to autoimmune disease.
Foreword
Cells are electrical devices.
This article presents an electrically oriented view of the cell,
with particular focus on the cell membrane. Autoimmunity, as conducted
by lymphocytes, B-Cells, T-Cells, and Natural Killer cells, generally
involves interactions of these cells with physical contact to evaluate
the health of other cells.
Figure
1: An immune cell
Autoimmunity is the army of cells
that patrol, evaluate, and eliminate "foreign" and "disruptive"
elements, in the continuing process of life and health. The traditional
view that these cellular interactions are chemical, and not electrical,
is strikingly limited. This article suggests the novel view that
most autoimmune disorders reflect a combination auto-electrical
dysfunctions combined with immunological insufficiency against an
undiagnosed pathogen.
Figure
2: Erythrocytes & WBC
This article presents the view
that autoimmune interactions are interactions are electrical, magnetic,
and paramagnetic, and chemical in nature. Modern research provides
at least 15 different field phenomenon, which in aggregate enable
a strikingly different modeling for immunological cellular interaction.
Figure
3: Magnetic Spin Illustration
The traditional view that autoimmunity
is chemically mediated – and the near absence of curative
progress in treatment of autoimmune diseases – suggests that
research and treatment, are misdirected. The purpose of this document
is to open a new chapter in autoimmune modeling.
The Cell Membrane
The cell membrane is the outside shell of the cell. It is very thin,
ranging from 3-8 nanometers. It hosts millions or billions of chemical
structures that implement the cell's role in the body.
Figure
4: Bilayer Membrane
The substrate is made of special
lipids or fats, which separate the inside of the cell from the outside
of the cell in a bilayer membrane. The membrane is special because
it is chemical and electrical.
Membranes are structural components of cells, fatty skeletons separating
water compartments. The exterior membrane encapsulates the exterior
of the cell and interfaces to cell-to-body functions.
Figure
5: Cell Membrane
The external membrane encapsulates
the cell, which in turn houses many other structures, many of which
are encased in cell membrane material.
Phospholipid structures provide the structure of the mitochondria,
which produce energy. In other words, cell membrane material is
a functional structure, providing both form and function to exterior
and interior cellular functions, including multiple energy production
processes.
Here
is a link to a truly excellent compilation of mitochondrial function
sponsored by Dr's Clark and Cargile. This is a 22,000 article compilation
of about 120,000 references. It is the place to start learning about
cellular energy production.
As an electrical element, the cell membrane is a semiconductor,
a capacitor, a resistor, and a battery. As a chemical entity, it
is simply indescribable.
The Basis of Power
The cell membrane is a chemical and electrical insulator. The inside
and outside of the membrane each host a pH differential. The pH
differential creates a voltage, or electricity. This electricity
is the power source for many essential functions in the cell membrane.
Figure 6: Chemical
Battery
Anything that compromises the
cell membrane power is a probable cause or cofactor in cellular
malfunction.
Compromise of either the cell
membrane quality or the transmembrane pH differential inhibits the
electrical functions of the cell and prevents optimal cell function.
Figure
7: Capacitor
The intracellular and extracellular
pH differential creates a voltage that provides chemical potential
or battery for cell membrane functions. This power supply is the
essential basis for hormone regulation, anabolic energy production,
and ionic cellular respiration.
Anything that causes the cell membrane to leak electricity drains
power. Both inadequate pH differential, and power leaks caused by
garbage lodged in membrane structures, interfere with cellular functions
that require power. When cell membrane power is down due to lipid
toxins or pH imbalances, cell just don't work. When cells don't
work, the body doesn't work.
Figure
8: Cell with internal lipid structures
There are three main aspects
of cell-membrane power production:
1. The lipid substrate – must insulate the inside and outside
and not leak power;
2. The pH differential – must be balanced to enable electricity,
just like a car battery;
3. Raw Materials -- must be present to create chemical and electrical
structures needed for the cell to work.
pH Culture
A cell's pH is utterly important because it enables the cell to
produce electrical power to drive membrane functions.
There is a tendency in health
care to focus on pH without considering the membrane integrity.
Singular focus on water chemistry tends to leave a big part of many
people's health problems improved, but unresolved.
Figure
9: pH of common substances
Both pH and water chemistry are
relatively easy to shift because the body's water compartments tend
to quickly exchange. Water-related protocols produce beneficial,
but short-term, results because they temporarily compensate for
other more structural or lipid dysfunctions. In other words, water
nutrient protocols increase cell voltage by temporarily improving
the ability to maintain pH inside and outside the cell.
Figure
10: Molecular binding
Unfortunately, water chemistry
leaves the cellular structural garbage in place, resulting in a
tendency for short-term benefits. Clearing both the membrane toxins
and the sources and restoring the cellular process of automatic
cleansing is critical to the durable restoration of cellular health.
Autoimmune Dysregulation
The autoimmune system protects the body from invasion and keeps
friendly organisms under control.The autoimmune system uses a library
of invader-sensing capabilities. It responds to invading pathogens
or overgrowth of symbiotic organisms, cells, bacteria, yeast, and
fungi, using many different and often barely understood sensing
mechanisms.
Figure
11: Autoimmune Memory Cells
Various forms of white blood cells, lymphocytes,
patrol the body continuously looking for imbalanced cells or organisms.
Immune patrol lymphocytes, B-Cells, and T-Cells, and Natural Killer
Cells maintain constant guard for invading or overgrown errant organisms.
Figure
12: Representation of TNF Alpha
Tumor Necrosis Factor Alpha is a member of
the TNF family of cytokines. This family of cytokines tag cells
for destruction by the immune system. They are created by macrophages
and other immune system cells.
TNF-Alpha are a special class of proteins called transmembrane proteins.
In simple terms, they reach through the cell membrane. The transmembrane
protein and transmembrane potential share the membrane dimension.
Figure
13: Transmembrane Structures span
cell membrane
This author suggests that the TNF triggers
apoptosis (cell death) when a cell membrane voltage drops below
a trigger threshold. TNF is therefore a defense mechanism against
diseases that result from cells that cannot maintain membrane power.
Electrically Mediated TNF Cancer Response
Healthy cells exist with a transmembrane potential of about 70 mV.
Cancer cells have a membrane potential from 15-30 mV. Since cancer
cells exist below the apoptosis trigger voltage, TNF is a front
line defense for cancer. TNF was named after it main role, triggering
death of cancer cells because of low cell membrane voltage.
TNF and Autoimmune Dysfunction
When cells membrane integrity deteriorates to a level near or below
the TNF activation, the autoimmune targeting of seemingly healthy
cells occurs, resulting in various autoimmune diseases. Tissues
targeted by autoimmune diseases tend to share relatively low levels
of oxygenation, as well as elevated cellular parasitism.
Individuals exposed to PEMF, or electromagnetic therapies, exhibit
often striking recoveries when energetics restore cellular immunity.
Pulsed fields in the range of 200 nS, with intensity from 2-5 Tesla,
often produce durable symptomatic reversal in less than six months.
Most subjects exhibit significant decrease in joint deformation
over about a four-month period.
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Before |
After four months |
Recovery is the likely result of healing that
appears to result because of decrease in sustained absence of localized
autoimmune activity, likely resulting from increased electro-positive
resistance to cellular parasites and probable energetic disadvantage
to the pathogens.
These results were the probable result of synergistic effects:
· Each exposure improved the transmembrane potential for
a period of one to three days, likely resulting in a tendency to
inhibit autoimmune TNF targeting;
· PEMF exposure increases tissue oxygen availability through
a variety of means, likely resulting in improved tissue oxygenation,
which enabled healing that would not have been otherwise possible;
· PEMF exposure was not limited to the hands, and the results
were consistent throughout the body.
PEMF Cellular Effect
Model
Pulsed electromagnetic fields create a significant turbulence at
the cellular level. Brief, sub-microsecond pulses generated when
electricity bridges a gap cause a short current to traverse a wire.
The short current causes a tendency for electricity to flow opposite
the current in the wire near the exposure. The result is a forward/backward
electricity flow in the tissues near the wire.
Figure
14: PEMF Coupling |
Figure
15: Magnetic Field around a
Wire |
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Cells in the vicinity of the wire appear to
absorb energy, usually obtaining a durable increase in transmembrane
potential normally observed as apparent performance improvement
in cell energetic structures, including, but not limited to, TNF
signaling.
In Vivo Pasteurization
Pulsed fields also exhibit destructive stress on certain microorganisms.
Click the links below to review National Institutes of Health (NIH)
references that indicate functional deactivation of various microorganisms
in food products:
· Saccharomyces cerevisiae, Alternate Article
· Salmonella Enteritidis
· Salmonella Enteritidis, E. coli and L. monocytogenes
· Escherichia coli, Listeria innocua and Saccharomyces cerevisiae
· Listeria Monocytogenes
· Escherichia coli, Salmonella Typhimurium and Listeria innocua
· Pseudomonas Fluorescens
· Lactobacillus plantarum
· Killing of Microorganisms by pulsed electric fields
· Mycobacterium paratuberculosis
Alert readers may perceive that the anti-microorganism effects of
pulsed fields are likely not limited to food products. These research
references strongly suggest that microbial deactivation is a by-product
of PEMF exposure. The results of the exposure are generally as follows:
· Proportional to the intensity of the PEMF pulse;
· Inversely proportional to the duration of the PEMF pulses
– shorter pulses exhibit stronger anti-microbial effects.
In other words, high-intensity short pulses do a better job of disrupting
microbial life cycle than low-intensity, long-duration pulses.
Figure
16: Pulse Waveform
PEMF exposure has the likely co-benefit of
inhibiting pathogenic microbes, hence reducing the load on the autoimmune
system.
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Author note: Artwork in this document is reproduced under GPL License
and may be reproduced from original sources at www.wikipedia.org.
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