June 2003
Coriolus versicolor Supplementation Study as Adjunct Nutrition in 30 Solid Tumour Cancer Patients
Editor:
Attached please find the final draft of Dr. Kenyon's non-controlled observational
study on the use of Coriolus versicolor (non-extracted) in 30 solid tumour
cancer patients. The final report will be published in the February edition
of Mycology News 7.
The patients were Stage III and Stage IV patients in which chemotherapy and
radiotherapy were not considered successful. Below please find a synopsis of
patient type.
Table 1
Patients by Tumour Type and Secondary Tumors
| Condition | Patients |
Secondary Tumors |
Number of Secondaries |
| Hodgkin's Lymphoma | 1 |
None |
0 |
| Prostate Cancer | 8 |
Bone |
6 |
| Bowel Carcinoma | 10 |
Liver |
9 |
| Breast Cancer | 8 |
Metastases |
8 |
| Died During Study | 3 |
n/a |
0 |
| Total | 30 |
23 |
The Coriolus supplementation was a biomass of the mycelia and primordial grown on a sterile substrate. Presentation was in tablets (1 tablet = 500 mg) and the schedule is given below:
Table II
Coriolus versicolor Supplementation
Schedule
| Grams per Day | |
| 1 Month 1 | 4.5 |
| 2 Month 2 | 9.0 |
| 3 Month 3 | 13.5 |
| 4 Month 4 | 13.5 |
Using the data points in 27 patients at day 0, 60 and 120, the objective
of the study was to measure the average change in four parameters over
the 120 period. The results were the following:
Table III
Summary of Results
| Day 0 | Day 60 | Day 120 | Average Change | |
| 1 Telomerase | 1727 | 1034 | 417 | -75.9% |
| 2 Interleukin 5* | 22540 | 28516 | 4482 | -80.1% |
| 3 Interleukin 12* | 13931 | 20968 | 29489 | 111.7% |
| Tumour Necrosis Factor | ||||
| 4 Beta*(1) | 27777 | 26113 | 31713 | 14.2% |
Dr. Kenyon felt that the results confirmed not only a general immune
support function but an increasing TH1 immune response which is beneficial
in such patient groups.
The average cost of Coriolus supplementation to a patient would be $560 over
16 weeks or $35 per week or $5.00 per day.
William Ahern, Managing Director
Mycology Research Laboratories
Bank House, Brough, East Yorkshire
HU15 1EF, United Kingdom
Telephone 44-1482-667-634
Fax 44-1482-667-859
www.mycologyresearch.com
info@aneid.pt
Dr. Kenyon operates the Dove Clinic for Integrated Medicine located in Hockley Mill Stables, Church Lane, Twyford, Hants, SO21 1NT, United Kingdom; telephone 44-1962-718-000; www.doveclinic.com
Mycology Research Laboratories Ltd. supplied the Coriolus versicolor for the trial (www.mycologyresearch.com).
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