Page 1, 2, 3, 4, 5,
In no sense is the writer to be understood as suggesting the hydrochloric
acid take the place of well-recognized directions for hygienic care,
diet, and other
measures found best for the particular case, but simply as adjuvant in the
demolition of pathological tissue, the repair of wounds, and the elimination
of harmful micro-organisms. A solution of 1-1000 U.S.P. hydrochloric acid
in distilled water has been found itself in 10 to 20 cc intravenous
this being the strength of this acid solution in the stomach.
The importance of the cellular fighting forces and agents of healing and
repair is conclusively shown by Dr. C.A. Doan, of Ohio State University
in a paper
on "The Neutropenic State," in which he says the following:
Roberts and Kracke were among the first to recognize the importance
of analyzing accumulated data in terms of white cell level and
symptomatology. In a review of the records of 8,000 private clinic patients,
1 out of every 54 was found to have a mild granulopenia; 1 out of every
2 women patients between the ages of 40 and 60 years was neutropenic;
and complaints of weakness exhaustion and fatigue were twice as frequent
in the granulopenic individuals as in those showing a normal white cell count.
Furthermore, the severity of the symptoms paralleled, to a remarkable extent,
the degree of granulopenia found.
Intravenous Hydrochloric Acid and Blood Transfusion
Through the kindness of Dr. George C. Williamson, of Columbia,
Tennessee, the following case report is made to illustrate the
in the blood pictures after the injection of hydrochloric acid and,
in the same case, the transfusion of blood, both procedures being
followed by a marked stimulation of the cellular forces.
On the night of April 4th, Dr. Williamson, in a talk over long-distance
telephone, told me he had a woman patient of 73, apparently in a
dying condition, with evidences of a marked abdominal infection,
and blood picture as shown in the chart (Table 3), with diagnosis
uncertain. I replied that I could give him no advice, but could only
what I would do were I present in Columbia, that I felt a marked
change could be made in blood picture by the injection of hydrochloric
Within ten days thereafter Dr. Williamson was so good as to send
charts with the information that the patient had died. The case is
reported to show the
failure of the measures taken in spite of the changes in the cells, as well
as an illustration of the changes in the blood that must have accompanied
the clinical results reported by another Tennessean in The Medical
World, Dr. W.
Table 3: Patient Chart
The King's Daughter Hospital
|April 3, 1933 3:00 p.m. 1,750
|April 4, 1933 9:00 a.m. 1,400 Neutrophiles- 1
|April 4, 1933 4:30 p.m. 1,750
|April 5, 1933 7:30 a.m. 4,900 Neutrophiles-52
|April 5, 1933 4:30 p.m. 8,600 Neutrophiles-60
|April 6, 1933 7:30 a.m. 20,100 Neutrophiles-79
|April 7, 1933 7:30 a.m. 26,650 Neutrophiles-79
|April 7, 1933 4:30 p.m. 19,950 Neutrophiles-88
|April 8, 1933 8:30 a.m. 31,600 Neutrophiles-89
|April 4, 1933 10 c.c. 1-1500 hydrochloric acid
|April 6, 1933 Transfusion 250 c.c. "whole blood."
I have never seen such changes in the
blood picture. These changes give a lucid explanation as to the reasons
for the results reported
by Dr. Howell and make publication useful, I would think.
One can get the same effect on the stimulation of the phagocytes by the injection
of 20 or 30 cc of blood intramuscularly. In such an injection, of course, no
examination of the blood of the donor is necessary save that it is clean and
free from any infection. So much time might be saved by the use of such an
injection of blood or the use of hydrochloric acid.
Stronger Solutions of Hydrochloric Acid
When nature developed hydrochloric acid in the evolution of animals by the
extraction of chlorine and hydrogen from food and drink for the maintenance
of the bloodstream's acid-base balance, a very peculiar acid was the
result. Its presence is essential to all glandular and cellular activity.
And the fascination of its use lies in the fact that laboratory determinations
are not necessary to confirm this statement. One may observe the changes
clinically, which, after all, furnishes the final test of any theory; for
example, no theory ever started its clinical test with more conclusive laboratory
proof than did the Ehrlich theory, and yet twenty-five years of faithful
trial were required before the conclusion was reached that the side-chain
theory was utterly worthless, thus taking its place along with all humoral
theories as a souvenir of past relief.
Dr. Paul Roth, of Battle Creek Sanitarium, found that after the injection
of 10 cc of 1-1000 hydrochloric acid intravenously the oxygen content of
was almost doubled 30 minutes after the injection. Hourly counts after an injection
will show the immediate effect in increasing the numbers of the white cells
and the quick correction of an improper balance as shown in the differential.
So when this basic body acid is injected, there is an immediate effect on the
oxygen content of the red cells, a phenomena that can only be explained by
some peculiar chemical effect on the acid-base balance. With the foregoing
facts and impressions as a basis, one may always find a case for illustration
of the many peculiarities of hydrochloric acid, an acid which I do not use
as a medicine, as I was taught to consider drugs. It cures no ailment known
to me but simply stimulates all the known and unknown forces of resistance,
the same forces that have earned nature the reputation of being the best of
doctors---the same forces that Hippocrates called "a vital spirit inherent
in all of us for the correction of ailments of our kind."
On September 22, 1934, a young man of 25, weighing 104 pounds, was brought
to me by his father. A well-established case of asthma, with a history of five-years'
duration, was given as the reason for the visit. In the piping voice of a little
boy, the anemic young man, with the characteristic prolonged expiration of
asthma, gave me haltingly the story of visits from his home in Oklahoma to
El Paso and Phoenix, Arizona. He reported temporary improvement in both towns
immediately after his arrival, but this helpful changes was soon replaced by
the same attacks of difficult breathing. In spite of a great quantity of mucus
in both lungs, as shown on auscultation, there was a little or no expectoration.
White cells were 7800 and red cells 3,200,000 per cubic millimeter, furnishing
an opportunity for increasing both white red cells by the injection of hydrochloric
Since the F.A.M.A. has so frequently given the opinion that injection of 1-1500
hydrochloric acid was dangerous in the great hemolysis following its intravenous
use, I decided to look for danger in this case, which I had done many times
before. So I gave 10 cc intravenously, 1-250 putting the remaining drop of
blood in acid solution on a slide at the finish of the administration of the
injection. Nowhere could one see any change in the contour of red cells. According
to the opinion from Chicago, I should have seen destructive change, but I did
The patient was asked to return the next day. This he did, and he told me that
he had never had such an expectoration. An examination of this sputum showed
a few streptococci and staphylococci and numberless white cells; it was not
necessary to confirm this stimulation of the white cells by counts. Clinically,
I have never seen such expectoration from infected lungs following the use
of expectorants as given in materia medica as one sees after hydrochloric acid.
Six injections of the 1-250 solution were given every seven days. After the
first week, there was a great decrease in the expectoration, a marked decrease
in the severity of the asthmatic attacks, a small increase in weight, and an
increase in strength. Before beginning the acid injections, he could not walk
one block without stopping one or more times for rest. At the end of the first
week, he could walk the block without discomfort. After sixty injections of
the acid, the patient was apparently free from asthma, but occasionally had
at night what he described as "wheezing" attacks, so the injections
were continued to try to eliminate the wheezing and get the weight back to
the original 140 pounds, as at this time he weighed only 120, a gain of 16
pounds under the influence of the acid-stimulated cells.
To my utter surprise, in late November, his appetite failed, and he began to
lose weight. Acid injections were continued as before. After a few days' steady
weight loss, a severe attack of asthma was reported, and he lost eight pounds
in weight. This was a therapeutic anomaly and, as I saw it, was only to be
met by the injection of more hydrochloric acid. However, stronger solutions
than 1-250 intravenously are painful at the site of injection and oftentimes
this pain is continuous for several hours up to the shoulder. So on December
1st, I gave more acid by making up a two-percent solution of Novocain and adding
hydrochloric acid to make a two-percent solution of the acid. To make it a
series of two's, two cubic centimeters were injected deep in a gluteal
muscle. About one-tenth of a cubic centimeter was first slowly injected and
was felt by the patient as a slight stinging sensation. After one minute, the
anesthetizing effect of the Novocain was in force, and the rest of the acid
solution was very slowly injected. The discomfort following was negligible.
Visits were made every 48-hours or three times a week; so that, today, he had
the eighth injection of the two-percent hydrochloric acid in Novocain solution.
His clinical behavior has proved the truth of the reason for the change; that
is, that the only medicine better than hydrochloric acid is more of it.
Today, the patient weighs 118 pounds, has not had an attack of asthma this
month, has walked three miles a day to make the visits here; hemoglobin is
90, red cells 4,770,000 per cubic millimeter; white cells 8400 before the injection
of the acid.
As an indication of the behavior of the white cells under the influence of
the acid injections, a count was done on the morning of the third visit, after
two injections of the 1-250 solution, and was 10,400. So I felt fairly sure
of the ultimate results after seeing this increase of 2,600,000 white cells
to the liter of blood over the first count, 48 hours before, of 7,800. As I
see it, these counts illustrate vividly the power of the basic body acid to
stimulate the one constant factor in resistance -- phagocytosis.
With the check in clinical improvement and loss of weight after two months
of the intravenous injections and the immediate change for the better under
the influence of the stronger solution intramuscularly, I feel it must be attributed
to a direct effect on the acid-base balance of the blood stream. At any rate,
the clinical behavior of this patient shows that this intramuscular injection
is more potent than the intravenous administration of the acid, in some cases.
The change in the voice of this patient has been quite as marked as that in
the red count. As mentioned before, on the first visit he had the voice of
a small boy. Within two weeks, it would have been noted as sonorous and deep
in "Fultah Fisher's boarding house." The disappearance of the anemia,
I think, is to be accounted for by doubling the oxygen content of the blood
six times a week and by the added activity to the phagocytes in neutralizing
the toxins or eliminating the germs causing the asthma.
There have been no inflammatory reactions or any discomfort attributable to
the injections of the hydrochloric acid, and, in passing, I might also say
I have given, after Novocain, this intramuscular injection as strong as ten
percent, 2 cc. The opinion of the colleague in the Association journal as to
the danger of the injection of hydrochloric acid is wrong.
Page 1, 2, 3, 4, 5,